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Institution Contacts

Greenville Health System  

Jean Winter

Medical University of South Carolina  

Stacey Goretzka

Palmetto Health

Mary Prather

Spartanburg Regional Healthcare System    

Frank Stewart

University of South Carolina    

Lisa Johnson

Health Sciences South Carolina


Health Sciences South Carolina (HSSC) electronic Institutional Review Board (eIRB) application for managing the Institutional Review Board (IRB) process for human subjects research that provides a single platform to unify and streamline the IRB operations of the five participating institutions.

The HSSC eIRB is a web-based system for IRB submissions, review, and management. It is a paperless, electronic method to submit, track, and route all submission types through the approval process and provides a means to document information required for the review of human subjects research. This includes the initial application, amendments, reportable events and continuing renewal submissions.


Users must be affiliated with one of the HSSC institutions available from the drop down list presented on the HSSC Federated login page found at

First time users of the system will be prompted to complete a registration page to be verified by the eIRB administrator at their respective institution which is required in order to activate their account.

Once access is authorized, new users will receive a confirmation email from their eIRB administrator.

Training and Education

After logging into the eIRB system, an “Education and Training” tab will be available and includes:

  • Study ‘States’ Guide
  • Quick Reference Guides for Research Activities
  • Quick Reference Guides for Protocol Navigation
  • External IRB Review Requests: Guidance for research staff
  • posting instructions
  • Study Sites and Multiple Sites Smartform: Guidance for research staff
  • Highlights: Cooperative Review Process for researchers


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